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Because clinical studies are conducted under widely varying conditionsadverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in practice.

Many of the patients who have developed rhabdomyolysis on therapy with simvastatin have had complicated medical historiesincluding renal insufficiency usually as a consequence of long-standing diabetes mellitusSuch patients taking Delivery lincocin VYTORIN merit closer monitoring.

Stop taking ezetimibe and simvastatin and call your doctor at once if you have any of these serious side effects:

In postmarketing experience with ezetimibecases of myopathy and rhabdomyolysis have been reportedMost patients who developed rhabdomyolysis were taking a statin prior to initiating ezetimibeHoweverrhabdomyolysis has been reported with ezetimibe monotherapy and with the addition of ezetimibe to agents known to be associated with increased risk of rhabdomyolysissuch as fibric acid derivativesVYTORIN and a fenofibrateif taking concomitantlyshould both be immediately discontinued if myopathy is diagnosed or suspected.

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